Fundamental and applied research in tasks of medical diagnostics is important because abnormal hemoglobins (nowadays more than 300 of them are known) lead to multiple pathological changes in a human organism which lead to different complications – lungs infarction, brain infarction, urinary diseases, cholelithiasis and others. Direct hemoglobinopathies are also well known, such as sickle cell disease, thalassanemia (the percentage of people suffering from thalassanemia is rising in Russia in the last decades). However, up to the present moment the latest scientific achievements practically have not been used in the diagnostics of these diseases.

A new scientific multidisciplinary fundamental and applied area “Fundamental and applied research of hemoglobin properties in medical diagnostics tasks” has been formed as a result of effective cooperation between MEPhI (“Computer medical systems” department), the Bach Institute of Biochemistry of RAS (laboratory of biochemistry of nitrogen fixation and nitrogen metabolism), N.N. Blokhin Russian Cancer Research Center (clinicodiagnostic laboratory), and “Professional development institute” FMBA of Russia (clinical diagnostics department) in 2013-2015.

MEPhI achievements have been used in solving difficult multifactorial multidisciplinary tasks of image recognition using expert technologies for making diagnostic medical decisions in a context of uncertainty, The Bach Institute of Biochemistry of RAS achievements in the research of hemoglobin properties, building mechanisms of hemoglobin modifications and the influence of external factors on the molecules of different hemoglobins. The laboratory of biochemistry of nitrogen fixation and nitrogen metabolism of the Bach Institute of Biochemistry of RAS cooperates with a range of leading scientific centres. There we should mention the group of Professor Stefano Bruno from University of Parma (Italy) and a team under the supervision of Professor Paul Thornalley from University of Warwick (Great Britain).

Junior research fellow of the Bach Institute of Biochemistry Elvira Nasibullina has been directed to study at the “Computer medical systems” department as a part of getting Master’s degree. New important results have been obtained during her studying and graduating with honours which were approved at joint seminars of MEPhI “Computer medical systems” department and the laboratory of biochemistry of nitrogen fixation and nitrogen metabolism of The Bach Institute of Biochemistry of RAS. The work has been represented at MEPhI academic sessions and two international conferences, and published in a scientific journal indexed in international databases «Web of Science» and «Scopus».