MEPhI is taking part in research in the following frameworks:

• federal targeted programs of the Ministry of Science and Higher Education of the Russian Federation, the Ministry of Health of the Russian Federation
• departmental programs of the State Atomic Energy Corporation "Rosatom"
• the Russian Federal Space Agency
• fundamental research programs of the Russian Science Foundation, the Russian Foundation for Basic Research, and the Russian Humanitarian Foundation.

Moreover, MEPhI put measures into effect in reply to the decisions of the Government of Russian Federation aimed at the attraction of leading Russian and foreign scientists to work at Russian institutions of higher education, as well as at the strengthening of cooperation between Russian higher education institutions and organizations that implement integrated projects for high-tech production.

Finally, MEPhI receives grants to support undergraduate and graduate students, young scientists, candidates and doctors of sciences, as well as leading scientific schools of the Russian Federation, as approved by the Council for Science of the Russian President and the Government of the Russian Federation.